Saturday, September 28, 2013

Cat's whiskers tea ( Orthosiphon stamineus ) active against colon cancer is not genotoxic.

Studies of Cat's whiskers tea ( Orthosiphon stamineus ) pharmacological profile have revealed antioxidant properties and other potentially useful biological activities. A study http://www.ncbi.nlm.nih.gov/pubmed/22136553 demonstrated that leaf extract inhibits growth of colon tumor and proliferation of blood vessels in mice.

But what about the genotoxic potential of the plant ?  it poses no genotoxic risk says an other study http://www.sciencedirect.com/science/article/pii/S0378874110007658
in which Orthosiphon stamineus extract was administered by gavage up to 4000 mg/kg body weight/day for 3 days : salmonella/microsome mutation assay and the mouse bone marrow micronucleus test did not indicate induced chromosome damage.

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